Executive Team and
Scientific Leadership

We are a team of seasoned biotechnology professionals with significant experience developing and launching leading pharmaceutical products.

Executive Team

Rob Etherington

Position: President & Chief Executive Officer

Mr. Etherington brings more than 28 years of sales, marketing and leadership experience in the pharmaceutical industry to Clene. Prior to joining Clene as CEO, Mr. Etherington worked for Actelion Pharmaceuticals, which was the largest biopharmaceutical company based in the EU until Johnson & Johnson Pharmaceuticals acquired the company in 2017. He initially joined Actelion as founding Director of Marketing in 2000, the same year the company went public, and went on to hold various roles of increasing responsibility. Mr. Etherington served as the first U.S. commercial employee, leading U.S. commercial operations and serving as Chair of the U.S. Commercial Strategic team where he was responsible for five marketed drugs. Prior to Actelion, Mr. Etherington began his pharmaceutical career with a number of sales and marketing roles at Parke-Davis, a division of Pfizer, culminating in a Team Leader position that oversaw the drug Lipitor. As the founding CEO of Clene, Mr. Etherington has raised more than $130M in equity financings, and has driven Clene’s focus on neurodegenerative diseases.

Mr. Etherington brings more than 28 years of sales, marketing...

Rob Etherington

President & Chief Executive Officer

Mark Mortenson

Position: Chief Science Officer

Mr. Mortenson is the co-inventor of the technology platform developed to produce Clene’s Clean-Surface Nanocrystal (CSN™) therapeutics, as well as the inventor/co-inventor for 30 other U.S. patents and hundreds of corresponding foreign patents.

Prior to joining Clene, Mr. Mortenson served as former Chief Operating Officer of Research, Development and Manufacturing for an advanced materials-based company of more than 300 employees. In addition to his professional experience, he is a former chief patent counsel responsible for approximately 5,500 patents and patent applications in the U.S. and 44 foreign countries. Mr. Mortenson holds both a Bachelor of Science in physics and a Bachelor of Science in ceramic engineering from Alfred University, a Master of Science in material science from Pennsylvania State University, and a Juris Doctor degree from George Washington University.

Mr. Mortenson is the co-inventor of the technology platform developed...

Mark Mortenson

Chief Science Officer

Robert Glanzman M.D., FAAN

Position: Chief Medical Officer

Dr. Glanzman brings to Clene more than 20 years of industry and medical practice experience. Prior to joining the company, Dr. Glanzman served as Chief Medical Officer for GeNeuro S.A., a Swiss-based, clinical stage pharmaceutical company developing treatments for patients with autoimmune diseases, including multiple sclerosis. Earlier in his career, Dr. Glanzman was recruited by the Roche Group as Global Development Team Leader for the ocrelizumab (Ocrevus) program from the end of Phase II through the initiation of Phase III, in 2012. Before his time with Roche, Dr. Glanzman worked for Novartis where he oversaw the successful Phase III development of fingolimod (Gilenya) and the commercial launch of interferon beta-1b (Extavia), in the U.S., and prior to this role, he spent eight years at Pfizer as Senior Medical Director and Team Leader of the medical affairs team for interferon beta-1a (Rebif). He has also held positions of increasing responsibilities at Purdue Pharmaceuticals and Nektar Therapeutics.

Before joining the industry in 1999, Dr. Glanzman spent seven years as an Assistant Clinical Professor at Michigan State University, where he led a busy clinical practice, taught residents and acted as principal investigator for numerous clinical trials. Dr. Glanzman is board certified in neurology and is a Fellow of the American Academy of Neurology. He earned his medical degree from Wake Forest University, completed a residency in neurology at the University of Michigan and completed his fellowship training in diagnostic nuclear medicine at Duke University.

Dr. Glanzman brings to Clene more than 20 years of...

Robert Glanzman M.D., FAAN

Chief Medical Officer

Ted Jeong, DM

Position: Chief Financial Officer

Dr. Ted (Tae Heum) Jeong has more than 20 years of experience as a venture capitalist and a financial executive. He is a Managing Partner at Kensington-SV Global Innovations LP, a growth-stage investment firm which he co-founded in 2018. Before becoming CFO of Clene, Dr. Jeong was CFO of Rexahn Pharmaceuticals, Inc. (Nasdaq: REXN), an oncology and CNS-focused biopharmaceutical company, from 2002 to 2018, where he completed equity financings totaling more than $170 million and was also responsible for forming strategic alliances and executing license deals in the U.S., Europe, and Asia. From 1997 to 2002, he served as the Senior Investment Manager at Hyundai Venture Investment Corporation, a subsidiary of the Hyundai Motors conglomerate and one of the largest venture capital firms in South Korea, where he operated two of the first healthcare venture capital funds in Korea. From 2019 to 2021, he also served on the board of directors of Neurobo Pharmaceuticals (Nasdaq: NRBO), where he was chair of the audit committee. Dr. Jeong received his bachelor’s and master’s degrees of science in chemistry from Pohang University of Science & Technology. He also holds a master of science in finance degree from Johns Hopkins University, and a doctorate of management from the University of Maryland.

Dr. Ted (Tae Heum) Jeong has more than 20 years...

Ted Jeong, DM

Chief Financial Officer

Michael Hotchkin

Position: Chief Development Officer

Mr. Hotchkin brings more than 20 years of experience in pharmaceutical commercialization, planning, strategy development, and medical affairs to Clene, where he currently leads commercial planning and strategy development, preclinical translational medicine, and health regulatory authority filings. Prior to joining the company, Mr. Hotchkin was a founding team member at Actelion Pharmaceuticals US, Inc., where he helped launch multiple best-in-class products for orphan disorders. Having spent more than a decade at Actelion, Mr. Hotchkin led the commercialization efforts for the company’s Genetic Business Unit, including clinical development activities which resulted in the doubling of sales for two different pharmaceutical drugs. Among his contributions while at Actelion include the implementation of new market planning activities for the company globally, directing U.S. strategy development and leading marketing activities for multiple medicines. Mr. Hotchkin began his career at Parke-Davis, a subsidiary of Pfizer.

Mr. Hotchkin brings more than 20 years of experience in...

Michael Hotchkin

Chief Development Officer

Jerry Miraglia J.D.

Position: General Counsel and Corporate Secretary

Mr. Miraglia has advised small private companies and large public companies, ranging from startups with only an idea to Fortune 125 companies. Most recently, he led the M&A legal team at Jabil Inc (NYSE: JBL), a contract manufacturer with 250,000+ employees operating in 30+ countries, including its medical solutions healthcare division. Mr. Miraglia spent the first 14 years of his legal career in Baltimore, joining Miles & Stockbridge out of law school and becoming a full equity partner in their corporate department, advising such clients as Black & Decker. Mr. Miraglia left Miles to serve as General Counsel for an interactive entertainment company, and subsequently entered the business world and served as EVP for Dover Motorsports (NYSE: DVD) and ultimately President of a media company. Mr. Miraglia’s diverse background navigating both business and legal aspects of corporate transactions, manufacturing, sales, marketing and distribution, providing Clene with a unique blend of insights as it leaves the private sector and enters the public.

Mr. Miraglia has advised small private companies and large public...

Jerry Miraglia J.D.

General Counsel and Corporate Secretary

Mary Anne McNeil

Position: Head, Human Resources

Mary Anne McNeil is the Head of Human Resources at Clene. Ms. McNeil is an accomplished professional with a diverse and successful career in human resources, management and marketing. Prior to joining Clene, Ms. McNeil served as the EVP of Human Resources, Marketing and Sales for a successful art business, where she executed a company culture of diversity, career development, and an outstanding sales force. While there, sales increased by 40%, the employee retention rate doubled and the signing of new artists to represent increased by over 12%. Ms. McNeil is creating a company culture which encourages diversity, growth and learning, open communication and accessibility, recognition for exemplary work, long term careers while striving to make Clene a leading and desirable place of employment. She has started a management training program by working with a local college, has implemented a review and raise process, has encouraged career mapping with all Clene colleagues which has led to many promotions within the company, assisted in developing a comprehensive training program and is working with workforce services to employ individuals from the local area. doubled. She is excited for the future of Clene and looks forward to its success and many upcoming milestones.

Mary Anne McNeil is the Head of Human Resources at...

Mary Anne McNeil

Head, Human Resources

Leadership

Mario Duprey

Position: Executive Director, Production and Manufacturing

Mario Duprey is the Executive Director of Production and Engineering at Clene. Mr. Duprey is an experienced leader in operations, manufacturing and quality. Mr. Duprey started his career at Glaxo-SmithKline where he spent 15 years learning, developing, and honing his skills in the areas of manufacturing, technical support, product development, process improvement and formulations covering tablets, capsules, liquids, ointments and suppositories and injectables. For the next 12 years, Mr. DuPrey was employed at Chr. Hansen, Inc. where he held progressive leadership roles in operations, technical sales and support, and quality in multi-site operations. Following his employment at Chr. Hansen, he continued to hold leadership roles in the areas of operations, quality, and manufacturing as the Director of Operations at Verion Pharmaceuticals, Inc., Senior Manufacturing Manager at Shire Pharmaceuticals, and Manager of Quality and Productivity at Evonik Corporation overseeing multiple sites with North America operations. Mr. Duprey’s skill set encompasses a well-rounded, in-depth understanding of manufacturing, formulations, and technical support in the pharmaceutical industry as well as the important synergy and operations on the ingredient supplier side.

Mario Duprey is the Executive Director of Production and Engineering...

Mario Duprey

Executive Director, Production and Manufacturing

Karen S. Ho, PhD

Position: Senior Director of Translational Medicine

Dr. Karen S. Ho is the Senior Director of Translational Medicine at Clene. Dr. Ho is responsible for translating preclinical successes of Clene’s lead drug assets into high medical value with applicability to multiple disease areas.  Dr. Ho is also responsible for biomarker development, scientific collaborations, presentations, publications, and grant writing. Prior to Clene, she was the lead scientist at a startup diagnostic testing company, where she streamlined and innovated new methodologies for the scientific interpretation of genetic testing results for children with autism, developmental delays, and/or cognitive impairment. After receiving her BS in Biochemistry summa cum laude from Washington University as a Compton Scholar, Dr. Ho lived in England for two years where she earned a MS in Genetics from the University of Cambridge as a Marshall Scholar. She has a PhD in Developmental Biology from Stanford and completed her postdoctoral training as a National Sleep Foundation Pickwick Scholar and Howard Hughes Medical Institute Postdoctoral Fellow at University of Pennsylvania in the Department of Neuroscience. Dr. Ho serves on several rare disease group Scientific Advisory Boards and holds a concurrent position as adjunct faculty at the University of Utah School of Medicine in the Department of Pediatrics, Division of Medical Genetics.

Dr. Karen S. Ho is the Senior Director of Translational Medicine...

Karen S. Ho, PhD

Senior Director of Translational Medicine

Austin Rynders

Position: Senior Director of Clinical Operations

Austin Rynders is the Senior Director of Clinical Operation at Clene. Mr. Rynders is a multi-faceted professional with over 10 years of clinical experience heavily focused in CNS/pain methodology with an emphasis in investigational pain modeling, abuse potential, degenerative disorders, and unique early proof-of-concept study development across Phase I-III studies. With participation and oversight of over 200 clinical trials prior to joining Clene, Mr. Rynders’ exposure to complex and unique study designs has allowed for development of a robust clinical mindset and multiple key accomplishments. These accomplishments include the development and implementation of validated methodologies surrounding ventilatory responses to hypercapnia and quantitative sensory testing, development and beta testing of cognition-based assessment platforms, operational reorganization of multiple clinical operations teams, and the expansion and development of a purpose built 136 bed Phase 1 facility. Mr. Rynders has received a Bachelor of Nursing from the University of Utah and will soon obtain his Master of Science in Pharmacology and Toxicology from Michigan State University.

Austin Rynders is the Senior Director of Clinical Operation at...

Austin Rynders

Senior Director of Clinical Operations

D. Kyle Pierce

Position: Executive Director Nano-Engineering

D. Kyle Pierce is the Executive Director of Nano-Engineering at Clene. Mr. Pierce has been with Clene since its inception. Mr. Pierce oversees the R&D department, designed the production equipment and software which Clene uses in its manufacturing of their key asset, and developed production procedures. He started his carrier in an antecedent technology and development company, General Resonance, as a Senior Engineer developing the technology used for Clene’s production equipment. While attending the University of Maryland at College Park, where he received a BS in Electrical Engineering, he worked for the Army Material System Analysis Activity (AMSAA DoD). While at AMSAA Mr. Pierce debugged and maintained an active protection performance model software, he was issued a Secret Security Clearance from the Department of Defense. While at Clene, he has co-authored numerous peer reviewed publications.

D. Kyle Pierce is the Executive Director of Nano-Engineering at...

D. Kyle Pierce

Executive Director Nano-Engineering

Adam Dorfman

Position: Executive Director of Quality Control and Bioanalytical

Adam Dorfman is the Executive Director of Quality Control and Bioanalytical at Clene. Mr. Dorfman has over 13 years of experience in various roles including nanoparticle development and characterization, specimen bioanalysis, and quality control. Mr. Dorfman has been with Clene since 2013 and is responsible for ensuring that the finished pharmaceuticals meet all quality standards for Clene’s active clinical trials. In addition, he leads the bioanalytical group that analyzes all GLP/GCP tissue and pharmacokinetic specimens that are collected during pre-clinical and clinical activities. Mr. Dorfman was originally tasked with establishing a GMP/GLP compliant lab at Clene, and more recently has been responsible for developing and implementing Clene’s laboratory informatics system that will streamline all manufacturing and quality control processes. He has a BS in Chemical Engineering from The Pennsylvania State University and MS in Chemical and Biomolecular Engineering from Johns Hopkins University.

Adam Dorfman is the Executive Director of Quality Control and...

Adam Dorfman

Executive Director of Quality Control and Bioanalytical

Rowena Green

Position: Senior Director of Quality Assurance

Rowena Green joined Clene Nanomedicine, Inc. in 2015, with experience in the (bio)pharmaceutical, nutraceutical, medical device and environmental industries. With over twenty-three years of GxP experience, eighteen years are as a quality assurance representative, which confirms her role as Sr. Director of Quality Assurance. Prior to Clene, Rowena spent three years as a consultant at Meridian BioGroup. There, she supported multiple clients to ensure compliance to the appropriate regulations (i.e., GMPs, GLPs). Prior to being a consultant, Rowena worked with Johns Hopkins University as the Quality Manager of the Cell Processing and Gene Therapy Department, which manufactured clinical trial material for multiple JHU Investigators. With a Bachelor of Science Degree in Chemistry, Rowena has worked as a Manufacturing Operator to produce brain cancer treatment, developed clinical trial projects to manufacture API as a Research Associate in Chemical Development, and performed the data review for one of the largest MRSA clinical studies ever conducted as a Sr. Quality Assurance representative. Rowena’s experience in the various industries has led her to Clene, where she and her direct reports provide regulatory support and quality assurance oversight for at least seven on-going clinical studies.

Rowena Green joined Clene Nanomedicine, Inc. in 2015, with experience...

Rowena Green

Senior Director of Quality Assurance

Joanne Zhongyan Zhang M.D., PhD

Position: Director of Micro and Biology

Joanne Zhongyan Zhang is the Director of Micro and Biology at Clene. Dr. Zhang has spent more than 20 years in medical research and is an experienced leader in quality control microbiology laboratory and scientific research in biology. Dr. Zhang helped design, and personally executed the initial and validated Cuprizone Studies of Clene’s asset, CNM Au8, suggesting that Au8 may enhance remyelination in MS. Dr. Zhang designed and directed the ALS pilot study proving that Au8 improved the motor coordination in congenic ALS SOD1 G93A mouse model. Both MS and ALS are now in Clinical Trial Phase II. Dr. Zhang brings to Clene both clinical experience and a successful medical research background. She spent over six years working as an attending physician and chief physician at Tianjin First Central Hospital. Dr. Zhang was a postdoctoral fellow in Cell Biology at Johns Hopkins University; she worked as research associate in the Cardiology Department at Duke University; and prior to Duke was awarded Special Fellow status by the Japan Society for the Promotion of Science while working at Osaka University. Dr. Zhang was awarded her medical degree from Tianjin Medical University and received her PhD from the Cardiology Division of Internal Medicine and Molecular Science at Osaka University.

Joanne Zhongyan Zhang is the Director of Micro and Biology...

Joanne Zhongyan Zhang M.D., PhD

Director of Micro and Biology

Matt Gardner CPA, J.D.

Position: VP Finance

Mr. Gardner has more than 20 years of experience in finance and accounting, including an extensive background in tax credits. Prior to joining Clene, Mr. Gardner worked for Blu., a Chinese energy sector start-up company, and served as Tax Director of UPS Freight, a North American division of UPS and multi-billion-dollar Fortune 100 global logistics company, from 2006 to 2012. Earlier in his career, he worked at KPMG and Ernst & Young, where he gained significant experience working with technology companies. Mr. Gardner is a certified public accountant, having earned his degree from the University of Utah, and is a licensed attorney, having earned his degree from Brigham Young University.

Mr. Gardner has more than 20 years of experience in...

Matt Gardner CPA, J.D.

VP Finance